NT scan low during pregnancy

Hi Doctor,
I am 16 weeks now. During 12 weeks I got my NT scan n corresponding blood test done.

All looks normal during the scan and NT value is 1.07 ,HcG is 0.32 and PAPP A is 0.82.
It seems that PAPP A value is slightly low.Risk is 1:100000. Please tell me is it a worrying factor that PAPP A value is slightly low. Please advice on low PAPP A.

 

NT scan low during pregnancy
Answered
Obstetrics & Gynae

Answers ( 3 )

  1. Hello Dear,

    Thank you for writing to us at MediMetry.

    Decreased levels of PAPP-A are found in association with abnormal placental function which has formed the basis for the first trimester screening of fetal Down syndrome. Low first trimester maternal serum levels are found not only in trisomy 21, trisomy 18 and trisomy 13, but also in non-Down syndrome fetal aneuploidies. PAPP-A is also said to have a positive relationship with birth weight. As PAPP-A decreases, the risk of small-for-gestational-age infants increases. PAPP-A levels in blood stream are found to be depressed in ectopic gravidity. Some of the complications associated with an unexplained isolated low PAPP-A are preterm delivery, intrauterine growth restriction, gestational hypertension, gestational hypertension with proteinuria.

    Hope this answers your query. Feel free to write back to us with follow-up questions.
    Stay connected to MediMetry for regular tips on safe & healthy pregnancy!
  2. User
    Can u tell me the average value of PAPP A value?
  3. Hello Dear,

    Thank you for writing back to us at MediMetry.
    There is exponential rise in pappa A level with gestational age. Its importance is between 11-14 week only.

    Hope this answers your query. Feel free to write back to us with follow-up questions.
    Stay connected to MediMetry for regular tips on safe & healthy pregnancy!