Can detect edward syndrome in USG during pregnancy?

Hello Doctor .
I delivery baby boy on 9th June 2016 and he was detected Edwards syndrome . My son died on 15th June 2016 . During pregnancy almost 7 ultrasound was conducted but radiologist was unable to detect and physical and organ deformities . I am 30 years and I am worried that if I try again for baby what are the chances of having second baby with edwards syndrome?
My another query is whether we should go for some treatment ? What was the reason that we had a baby with genetic abnormality?
When should I plan for second baby ?
What precaution we should take next time to avoid the above mentioned situation ?
Can radiologist detcte edwards syndrome through Ultra sound techniques?
planning family after miscarriage

Answered
Obstetrics & Gynae

Answers ( 8 )

  1. Dear Mayuri Good evening.First of all I feel sad that you have lost a beautiful son.
    Coming to other questions
    1) Let me know whether the baby was deliverrd normally or by C- section ,as you are already 30 yrs spacing between two pregnancy will depend on that
    2) This type of genetic abnormality is not common and it occurs due to translocation of gene and there is an extra chromosome either in ovum or sperm in preconception stage.For which nothing can be done.
    3) Edward syndrome is more common in female than in male babies.
    4)There is no hard and first rule that if one child is affected the next one will also be affected. Recurrence is not that common.
    5)Pl.let me know the age of your husband and his occupation and whether he is having any medical disorder.
    Coming to your other queries I am forwarding the following details.
    Screening for Edwards' Syndrome

    Pregnant women are offered a screening test for Edwards' syndrome and from 10-14 weeks of pregnancy. This is to assess your chance of having a baby with these conditions.
    Edwards' syndrome is also called Trisomy 18 or T18,
    The screening test offered at 10-14 weeks is called the combined test. It involves a blood test and an ultrasound scan.
    If you are too far into your pregnancy in Edwards’ syndromes, you will be offered a mid-pregnancy scan that checks for physical abnormalities.
    If a screening test shows that you have a higher risk of having a baby with Edwards you will be offered diagnostic tests to find out for certain if your baby has the condition.

    Inside the cells of our bodies there are tiny structures called chromosomes. Chromosomes carry the genes that determine how we develop. There are 23 pairs of chromosomes in each cell.
    Problems can occur when sperm or egg cells are produced, which can lead to a baby having an extra chromosome.

    In Edwards' syndrome, there is an extra copy of chromosome 18 in each cell.
    Sadly, most babies with Edwards' or syndromes will die before they are born or die shortly after birth. Some babies may survive to adulthood, but this is rare.
    All babies born with Edwards' syndromes will have a wide range of problems, which are usually very serious. These may include major brain abnormalities.
    Babies affected by Edwards' syndrome can have heart problems, unusual head and facial features, growth problems, and be unable to stand or walk. Edwards' syndrome affects about 3 out of every 10,000 births.
    Babies affected by Edwards' involve will require

    A screening test for Edwards' syndromes , available from weeks 10-14 of pregnancy. It is called the combined test because it combines an ultrasound scan with a blood test. The scan can be carried out at the same time as the pregnancy dating scan.
    If you choose to have the test, a blood sample will be taken from you. At the scan, the fluid at the back of the baby's neck is measured (known as the nuchal translucency). Your age and the information from these two tests is used to work out the risk of the baby having Edwards' syndromes.
    It is not always possible to obtain a nuchal transparency measurement, and depends on the position of the baby. If this is the case, you will be offered a different blood screening test to take place from weeks 14-20.
    If you are too far on in your pregnancy (more than 14 weeks) to have the combined test, you will be offered a test called the quadruple blood screening test from 14-20 weeks of pregnancy. This blood test only screens for Down’s syndrome and is not quite as accurate as the combined test.
    For Edwards' syndrome, if you are too far into your pregnancy to have the combined test, you will be offered a mid-pregnancy scan. This scan looks for physical abnormalities and 11 rare conditions, including Edwards’ and Patau’s syndromes and other conditions.
    It cannot tell you for certain if the baby has or does not have. Edward's Syndrome.
    N.B *****MediMetry is for Basic Consultaion.All informations given here is for informative purposes and should not be used for Medico legal purposes.
    All information should be corelated with clinical findings and for all purposes your Obstetrician should be consulted for advice and guidelines.
  2. User
    Thank you Dr Basu .
    My husband is 31 years old and he is working as scientist. I had undergo c section for delivery and intra uterine baby weight was low . During birth his weight was 2 kgs and his heart beat was 120 bpm.
    I did seven ultrasound 13 , 18 , 22 , 27 , 36 weeks consecutively. Still I am unhappy with outcome that radiologist was not able to detect and abnormality as aftter birth he suffered from VSD , PDA , Cleft palate , inguinal hernia , micrognathia , twisted wrist and many more.
    If I could have detected thsee problems during antenatal or prenatal screening . I could have terminated the prenancy .
  3. Dear Mayuri.I have no word to sympathise with you.Where do you stay? Will you please tell me why C-section was done?
    Coming to USG it may not diagnose all the congenital diffect but gives an indication of the risk involved whether high or low and certain congenital defects as you have mentioned could have been detected I presume and if doctor is having any doubt other tests could have been done with your consent.
    Since you had a C-section although your age is 30yrs you should give some time for the uterine scar to heal .
    In the mean time you two have Karyotyping done.
    Avoid sedatives and addiction producing medicines.
    Have your husband's semen analysed after abstinance of 15days.
    Please don't get worried or tensed as these have adverse effect on ovulation.
    You must consult a good Obstetrician for pre-conception counselling before you plan for next pregnancy.
    why so many USG done did your doctor had any thing abnormal in his mind.Did you have all the USG done from the same clinic.
    Was it mentioned any time for anomaly scan in the advice given at 13,18 & 22 wks

  4. User
    Thank you sir , for your immediate guidance and support. I stay in Gujarat but for delivery I travelled all the way from Gujarat to Chhattisgarh Raipur . As this was my first child so everyone suggested for parents home for better care. My father is a doctor too with 33 years of practice and he is specialied in Gastrointestinology .
    Gynecologist told me that normal will be very painful for you so it's better to plan for c section in advance. I completed my full term but there was no pain . Many time I complaint to gynecologist that I can't feel baby movement. She use to palpate my abdomen and she always suggested to repeated ultra sound thus I had to do so.
    Mostly I complaint for lower abdominal pain as well as pain in pelvic and groin region. But doctor told me that this common during pregnancy.
  5. Dear Mayuri Good Evening I really feel bad for what has happened to you.
    Don't get preoccupied of what has happened.Next time opt for a senior gynarcologist of a medical college
    I Think she for got to mention the word "anomaly scan"
    I am in the profession for a long time precisely since 1969 and I can say repeatation of Edward Syndrome is rare and affected child are usually female and is due to preconceptional genetic disorder.
    However in next pregnancy please get an anomaly scan done
    between 11 to 14 wks and between 18 to 22 wks.
    Best wishes to you and kind regards to your father.
    Pl.let me know Your father's name . Did he graduated from Calcutta ?
  6. *** correction **Graduate
  7. User
    Thank you Sir,
    My father's name is Dr Kanchan Banerjee . He did his MBBS from Jabalpur medical college . Presently my father own his clinic in Raipur Chhattisgarh.
    My brother in law is doing internship from KPC medical college from Calcutta .
    For next time surely I will take all kind of precaution .
  8. You are welcome.Keep in touch. If any problem don't hesitate to contact me.Best wishes.